Spago verifies nanoparticle properties at Maxlab.

Spago has verified size, composition, and manganese coordination geometry for the Spagopix MRI contrast agent. The results were generated in collaboration with the scientists at Maxlab in Lund, Sweden. The techniques used were XAFS and SAXS, both utilizing the high intensity, monochromatic X-rays generated by the Maxlab accelerator. Size and composition had been measured before by other methods but the data generated now are complementary (core size 4 nm) and build a stronger case in discussions with potential licensees of the contrast agent. As for the coordination geometry it had previously only been predicted by high level ab-inito, quantum chemistry calculations and the results were found to be in excellent agreement. The results verify that Spagopix has desirable properties for tumor imaging and renal excretion.